Place of Practice


Practice Address

Mount Elizabeth Novena Specialist Centre
38 Irrawaddy Road, #06-39, Singapore 329563

Tel :(65) 6250 2500

24 Hour Hotline: (65) 6535 8833

Practice Website


Senior Consultant General and Interventional Cardiologist


MBBS(Singapore), FAMS(Cardiology)(Singapore),MRCP(UK), FRCP (Edin), FACC (USA), ACSM (USA)

About A/Prof Ooi

Dr Ooi Yau Wei is the Medical Director at Sozo Cardiology Clinic and a Consultant General and Interventional Cardiologist with more than 15 years of clinical experience. He graduated from the Yong Loo Lin School of Medicine, National University of Singapore in 1999 with a Bachelor of Medicine and Surgery (MBBS) and obtained his post-graduate Internal Medicine degree, Membership of the Royal College of Physicians (United Kingdom) in 2004. He has worked in Tan Tock Seng Hospital (TTSH) since 1999 and received the SARS Courage Star award from the President of Singapore in 2003 for his work with SARS victims in the Intensive Care setting.

He underwent his Cardiology Advanced Specialty Training in Tan Tock Seng Hospital, Singapore from 2005-2008 and was inducted as a Fellow of the Academy of Medicine, Singapore (FAMS) in 2009. He subsequently spent a year running the largest Heart Failure Program in Singapore, managing patients with complex end-stage heart failure requiring electrical/mechanical assist device therapy and heart transplantation.

In 2010, he was awarded the Human Manpower Development Program (HMDP) scholarship by Ministry of Health, Singapore to further sub-specialize in the field of Interventional Cardiology at the University of British Columbia in Vancouver, Canada. He spent a year under the mentorship of 4 world-renown Professors and experts in Interventional Cardiology and was trained in the latest advances in the Interventional Cardiology arena. He gained extensive experience in treating patients with complex left main, bifurcation, bypass graft lesions and chronic total occlusions using the latest in adjunctive interventional techniques such as rotational atherectomy and coronary imaging eg Intra-Vascular UltraSound (IVUS) and Optical Coherence Tomography (OCT). He was also trained in carotid and peripheral artery stenting, left atrial appendage closure for stroke prevention and transcatheter aortic valve replacement (TAVR) in surgical turn-downs for severe aortic valve stenosis.

He subsequently returned to Singapore in 2011, working as a Certified Senior Interventional Cardiologist, providing 24/7 acute heart attack interventional service in TTSH. He has since taught in more than 10 interventional stenting workshops on advanced interventional techniques for doctors from Malaysia, Myanmar, Indonesia and Australia. To date, he has performed more than 6,000 invasive coronary angiography and percutaneous coronary intervention procedures, mostly through the less invasive radial (wrist) approach. He has also successfully treated many patients with resistant hypertension via non-invasive renal denervation device therapy.

Dr Ooi is a strong believer in minimally invasive angioplasty (stenting) using the radial (wrist) approach rather than the femoral (groin) approach as this increases patient comfort and safety while significantly reducing complications such as bleeding or death by as much as 30%. He also harnesses the latest in stent technology eg. using Bioresorbable Vascular Scaffolds (stents that dissolve away) to give his patients freedom from being “caged” permanently with a stent.

Apart from his interest in complex coronary intervention, his other interests include Sports Cardiology. He has been certified as a Clinical Sports Physiologist by the American College of Sports Medicine (ACSM) since 2014. Topics of relevance to the modern patient include prevention of sudden cardiac death and risk stratification for healthy subjects planning to undergo strenuous and extreme exercise.

Dr Ooi’s passion is in teaching. His past and present academic appointments include Head of Postgraduate Education in the Department of Cardiology, Program Director of the National Healthcare Group (NHG) Cardiology Senior Residency program, core faculty member of the Internal Medicine Residency program, Clinical Senior Lecturer at the Yong Loo Lin School of Medicine and Cardiology Lead at Lee Kong Chian School of Medicine (LKCSoM). In recognition of his contributions to education, he was appointed as Adjunct Asst Professor in Cardiology in LKCSoM.

Despite his move to private practice, he continues to nurture the younger generation of doctors by returning to TTSH weekly to mentor medical undergraduates, junior doctors in internal medicine, advanced cardiology trainees, nurses and allied health professionals.

Dr Ooi is also actively involved in clinical research and was the co-investigator in numerous international clinical trials like PLATO, IMPROVE-IT, GLOBAL LEADERS and LEADERS-FREE. He has written articles focusing on the management of acute coronary syndromes and coronary stenting, which have been published in international peer-reviewed journals. He is also invited regularly to be both speaker and faculty in major local and international cardiology conferences.
In recognition of his professional, educational and research achievements, and contributions to cardiovascular medicine, he was inducted as a Fellow of the Royal College of Edinburgh (FRCP) in 2010 and Fellow of the American College of Cardiology (FACC) in 2015.

On a more personal note, Dr Ooi believes in using his years of clinical experience to deliver the highest quality of clinical care to every patient, regardless of their socio-economic status. He is passionate about guiding patients to make a well-informed decision for their health which fits their values, preferences and goals. He believes in working honestly, ethically, with integrity and utmost sincerity. He aims to provide the highest level of cardiovascular care in a cost-effective manner. Ultimately, he treasures the long-lasting relationships he builds with all his patients.

Professional Appointments

Present Clinical and Academic Appointments

  • Adjunct Asst Professor, Lee Kong Chian School of Medicine
  • Consultant General and Senior Interventional Cardiologist
  • Clinical Senior lecturer, Yong Loo Lin School of Medicine, National University of Singapore (NUS)
  • Cardiology Lead, Lee Kong Chian School of Medicine
  • Clinical Core Faculty Member, National Healthcare Group (NHG) Cardiology Senior Residency Program
  • Advanced Cardiac Life Support Instructor

Past Appointments

  • Head of Post-Graduate Education, Department of Cardiology, Tan Tock Seng Hospital
  • Program Director, NHG Cardiology Senior Residency Program
  • Clinical Core Faculty Member, NHG Internal Medicine Residency Program
  • Chairman of Clinical Competency & Program Evaluation Committee, NHG Cardiology Senior Residency Program

Specialized Services

Cardiac Investigations

We offer comprehensive evaluation of patients with chest pain, shortness of breath, palpitations and fainting spells using only the latest state-of-the-art cardiovascular equipment. These provide highly valuable information in the overall diagnostic evaluation of our patients.

Non-invasive Cardiac Investigations

1. Electrocardiography

  • 12-Lead Electrocardiogram (ECG)
  • Signal-Averaged ECG
  • 24-hour Ambulatory ECG Monitoring
  • Exercise Stress ECG (Treadmill test)

2. Ambulatory Diagnostic Services

  • 24-hour Ambulatory Blood Pressure (ABP) Monitoring
  • Tilt-Table Test
  • Pacemaker check
  • Automated Implantable Cardioverter Defibrillator (AICD) check
  • Carotid Intimal Media Thickness
  • Comprehensive range of blood and urine investigations

3. Echocardiography

  • Trans-Thoracic Echocardiogram (TTE)
  • Trans-Esophageal Echocardiogram (TEE)
  • Exercise Stress Echocardiogram (ESE)
  • Dobutamine Stress Echocardiogram (DSE)

4. Nuclear Cardiac Imaging

  • Exercise Stress Myocardial Perfusion Imaging
  • Dobutamine Stress Myocardial Perfusion Imaging
  • Radionuclide Ventriculography
  • Myocardial Viability Studies

5. High-resolution Cardiac Computed Tomography (CT)

  • CT Coronary Calcium Scoring
  • Multi-slice CT Coronary Angiography

6. Cardiac Positron Emission Tomography (PET) Study


Specialized Cardiac Investigations

  • Coronary Angiography and Left Ventriculography
  • Right Heart Study
  • Endomyocardial Biopsy
  • Cardiac Electrophysiology Study


Cutting Edge Treatment

We provide specialist treatments for patients with complex coronary artery disease, heart failure, heart rhythm disorders, heart muscle and valve diseases, and difficult-to-manage cholesterol and blood pressure disorders. We also provide specialized procedures such as coronary angiography and stent insertion, pacemaker and cardiac defibrillator device implantation and catheter ablation of cardiac arrhythmias, using only the latest and most innovative equipment.

Specialized Cardiac Procedures

  • Coronary Angioplasty and Stenting (with Bare/Drug-eluting/Bioresorbable stents)
  • Fractional Flow Reserve (FFR) Study
  • Intra-Vascular UltraSound (IVUS) Study
  • Optical Coherence Tomography (OCT) Study
  • Insertion and removal of Loop Recorder
  • Pacemaker implantation
  • Automated Implantable Cardioverter Defibrillator (AICD) implantation
  • Cardiac Resynchronization Therapy (CRT) device implantation
  • Electrophysiology Study with/without radiofrequency catheter ablation
  • Renal Denervation Therapy

We work closely with expert cardiothoracic surgeons to provide cardiovascular support when cardiac surgery is needed so as to achieve the best surgical outcome.